@article{90986,
  keywords = {Animals, Humans, DNA Repair, DNA Damage, Telomere, Telomere-Binding Proteins},
  author = {Yun Wu and Virginia Zakian},
  title = {Identity crisis when telomeres left unprotected.},
  abstract = { Loss of shelterin components TRF2 or POT1a-TPP1 complex from the chromosome end triggers DNA damage response (DDR) and aberrant DNA repair events. In a recent Nature paper, Chang and colleagues reported that the DNA repair protein Mre11 contributes to multiple events at the uncapped telomere, including ataxia telangiectasia-mutated (ATM)-dependent signaling, processing of the telomeric G-tail and homologous recombination (HR). },
  year = {2010},
  journal = {J Mol Cell Biol},
  volume = {2},
  pages = {14-6},
  month = {02/2010},
  issn = {1759-4685},
  doi = {10.1093/jmcb/mjp031},
  language = {eng},
}