@article{91156, keywords = {Base Sequence, Molecular Sequence Data, DNA-Binding Proteins, Saccharomyces cerevisiae Proteins, Saccharomyces cerevisiae, DNA Repair, DNA Damage, Chromosome Deletion, Telomere, Recombination, Genetic, DNA Helicases, DNA, Fungal, Chromosomes, Fungal, Rad52 DNA Repair and Recombination Protein}, author = {Mangahas and Alexander and Sandell and Zakian}, title = {Repair of chromosome ends after telomere loss in Saccharomyces.}, abstract = { Removal of a telomere from yeast chromosome VII in a strain having two copies of this chromosome often results in its loss. Here we show that there are three pathways that can stabilize this broken chromosome: homologous recombination, nonhomologous end joining, and de novo telomere addition. Both in a wild-type and a recombination deficient rad52 strain, most stabilization events were due to homologous recombination, whereas nonhomologous end joining was exceptionally rare. De novo telomere addition was relatively rare, stabilizing }, year = {2001}, journal = {Mol Biol Cell}, volume = {12}, pages = {4078-89}, month = {12/2001}, issn = {1059-1524}, language = {eng}, }