Saccharomyces cerevisiae Proteins

Lin, and Zakian. (1994) 1994. “Isolation and Characterization of Two Saccharomyces Cerevisiae Genes That Encode Proteins That Bind to (TG1-3)n Single Strand Telomeric DNA in Vitro.”. Nucleic Acids Res 22 (23): 4906-13.

Reference Link
Schulz, and Zakian. (1994) 1994. “The Saccharomyces PIF1 DNA Helicase Inhibits Telomere Elongation and De Novo Telomere Formation.”. Cell 76 (1): 145-55.

Reference Link
Sandell, and Zakian. (1993) 1993. “Loss of a Yeast Telomere: Arrest, Recovery, and Chromosome Loss.”. Cell 75 (4): 729-39.

Reference Link
Wiley, and Zakian. (1995) 1995. “Extra Telomeres, But Not Internal Tracts of Telomeric DNA, Reduce Transcriptional Repression at Saccharomyces Telomeres.”. Genetics 139 (1): 67-79.

Reference Link
Balakumaran, Freudenreich, and Zakian. (2000) 2000. “CGG/CCG/Repeats/Exhibit/Orientation-Dependent/Instability/and/Orientation-Independent/Fragility/in/Saccharomyces/Cerevisiae.”. Hum Mol Genet 9 (1): 93-100.

Reference Link
Teng, and Zakian. (1999) 1999. “Telomere-Telomere Recombination Is an Efficient Bypass Pathway for Telomere Maintenance in Saccharomyces Cerevisiae.”. Mol Cell Biol 19 (12): 8083-93.

Reference Link
Stavenhagen, and Zakian. (1998) 1998. “Yeast Telomeres Exert a Position Effect on Recombination Between Internal Tracts of Yeast Telomeric DNA.”. Genes Dev 12 (19): 3044-58.

Reference Link
Bourns, Alexander, Smith, and Zakian. (1998) 1998. “Sir Proteins, Rif Proteins, and Cdc13p Bind Saccharomyces Telomeres in Vivo.”. Mol Cell Biol 18 (9): 5600-8.

Reference Link
Ivessa, Zhou, and Zakian. (2000) 2000. “The Saccharomyces Pif1p DNA Helicase and the Highly Related Rrm3p Have Opposite Effects on Replication Fork Progression in Ribosomal DNA.”. Cell 100 (4): 479-89.

Reference Link
Tham, and Zakian. (2000) 2000. “Telomeric Tethers.”. Nature 403 (6765): 34-5. doi:10.1038/47385.

Reference Link
Tsukamoto, Taggart, and Zakian. (2001) 2001. “The Role of the Mre11-Rad50-Xrs2 Complex in Telomerase- Mediated Lengthening of Saccharomyces Cerevisiae Telomeres.”. Curr Biol 11 (17): 1328-35.

Reference Link
Tham, Wyithe, Ko Ferrigno, Silver, and Zakian. (2001) 2001. “Localization of Yeast Telomeres to the Nuclear Periphery Is Separable from Transcriptional Repression and Telomere Stability Functions.”. Mol Cell 8 (1): 189-99.

Reference Link
Bessler, Torres, and Zakian. (2001) 2001. “The Pif1p Subfamily of Helicases: Region-Specific DNA Helicases?”. Trends Cell Biol 11 (2): 60-5.

Reference Link
Teng, Chang, McCowan, and Zakian. (2000) 2000. “Telomerase-Independent Lengthening of Yeast Telomeres Occurs by an Abrupt Rad50p-Dependent, Rif-Inhibited Recombinational Process.”. Mol Cell 6 (4): 947-52.

Reference Link
Zhou, Monson, Teng, Schulz, and Zakian. (2000) 2000. “Pif1p Helicase, a Catalytic Inhibitor of Telomerase in Yeast.”. Science 289 (5480): 771-4.

Reference Link
Qi, and Zakian. (2000) 2000. “The Saccharomyces Telomere-Binding Protein Cdc13p Interacts With Both the Catalytic Subunit of DNA Polymerase Alpha and the Telomerase-Associated Est1 Protein.”. Genes Dev 14 (14): 1777-88.

Reference Link
Callahan, Julie, Kenneth Andrews, Virginia Zakian, and Catherine Freudenreich. (2003) 2003. “Mutations in Yeast Replication Proteins That Increase CAG CTG Expansions Also Increase Repeat Fragility.”. Mol Cell Biol 23 (21): 7849-60.

Reference Link
Taggart, Andrew, and Virginia Zakian. (2003) 2003. “Telomerase: What Are the Est Proteins Doing?”. Curr Opin Cell Biol 15 (3): 275-80.

Reference Link
Alexander, Mary Kate, and Virginia Zakian. (2003) 2003. “Rap1p Telomere Association Is Not Required for Mitotic Stability of a C(3)TA(2) Telomere in Yeast.”. EMBO J 22 (7): 1688-96. doi:10.1093/emboj/cdg154.

Reference Link
Taggart, Andrew, Shu-Chun Teng, and Virginia Zakian. (2002) 2002. “Est1p As a Cell Cycle-Regulated Activator of Telomere-Bound Telomerase.”. Science 297 (5583): 1023-6. doi:10.1126/science.1074968.

Reference Link
Zhou, Jin-Qiu, Haiyan Qi, Vincent Schulz, Maria Mateyak, Ellen Monson, and Virginia Zakian. (2002) 2002. “Schizosaccharomyces Pombe pfh1+ Encodes an Essential 5’ to 3’ DNA Helicase That Is a Member of the PIF1 Subfamily of DNA Helicases.”. Mol Biol Cell 13 (6): 2180-91.

Reference Link
Ivessa, Andreas, Jin-Qiu Zhou, Vince Schulz, Ellen Monson, and Virginia Zakian. (2002) 2002. “Saccharomyces Rrm3p, a 5’ to 3’ DNA Helicase That Promotes Replication Fork Progression through Telomeric and Subtelomeric DNA.”. Genes Dev 16 (11): 1383-96. doi:10.1101/gad.982902.

Reference Link
Mangahas, Alexander, Sandell, and Zakian. (2001) 2001. “Repair of Chromosome Ends After Telomere Loss in Saccharomyces.”. Mol Biol Cell 12 (12): 4078-89.

Reference Link
Torres, Jorge, Sandra Schnakenberg, and Virginia Zakian. (2004) 2004. “Saccharomyces Cerevisiae Rrm3p DNA Helicase Promotes Genome Integrity by Preventing Replication Fork Stalling: Viability of Rrm3 Cells Requires the Intra-S-Phase Checkpoint and Fork Restart Activities.”. Mol Cell Biol 24 (8): 3198-212.

Reference Link
Torres, Jorge, Jessica Bessler, and Virginia Zakian. (2004) 2004. “Local Chromatin Structure at the Ribosomal DNA Causes Replication Fork Pausing and Genome Instability in the Absence of the S. Cerevisiae DNA Helicase Rrm3p.”. Genes Dev 18 (5): 498-503. doi:10.1101/gad.1154704.

Reference Link
Ivessa, Andreas, Brian Lenzmeier, Jessica Bessler, Lara Goudsouzian, Sandra Schnakenberg, and Virginia Zakian. (2003) 2003. “The Saccharomyces Cerevisiae Helicase Rrm3p Facilitates Replication past Nonhistone Protein-DNA Complexes.”. Mol Cell 12 (6): 1525-36.

Reference Link
Azvolinsky, Anna, Stephen Dunaway, Jorge Torres, Jessica Bessler, and Virginia Zakian. (2006) 2006. “The S. Cerevisiae Rrm3p DNA Helicase Moves With the Replication Fork and Affects Replication of All Yeast Chromosomes.”. Genes Dev 20 (22): 3104-16. doi:10.1101/gad.1478906.

Reference Link
Boulé, Jean-Baptiste, and Virginia Zakian. 2006. “Roles of Pif1-Like Helicases in the Maintenance of Genomic Stability.”. Nucleic Acids Res 34 (15): 4147-53. doi:10.1093/nar/gkl561.

Reference Link
Boulé, Jean-Baptiste, Leticia Vega, and Virginia Zakian. (2005) 2005. “The Yeast Pif1p Helicase Removes Telomerase from Telomeric DNA.”. Nature 438 (7064): 57-61. doi:10.1038/nature04091.

Reference Link
Fisher, Timothy, and Virginia Zakian. (2005) 2005. “Ku: A Multifunctional Protein Involved in Telomere Maintenance.”. DNA Repair (Amst) 4 (11): 1215-26. doi:10.1016/j.dnarep.2005.04.021.

Reference Link
Bessler, Jessica, and Virginia Zakian. (2004) 2004. “The Amino Terminus of the Saccharomyces Cerevisiae DNA Helicase Rrm3p Modulates Protein Function Altering Replication and Checkpoint Activity.”. Genetics 168 (3): 1205-18. doi:10.1534/genetics.104.028035.

Reference Link
Fisher, Timothy, Andrew Taggart, and Virginia Zakian. (2004) 2004. “Cell Cycle-Dependent Regulation of Yeast Telomerase by Ku.”. Nat Struct Mol Biol 11 (12): 1198-205. doi:10.1038/nsmb854.

Reference Link
Mondoux, Michelle, Jillian Scaife, and Virginia Zakian. (2007) 2007. “Differential Nuclear Localization Does Not Determine the Silencing Status of Saccharomyces Cerevisiae Telomeres.”. Genetics 177 (4): 2019-29. doi:10.1534/genetics.107.079848.

Reference Link
Boulé, Jean-Baptiste, and Virginia Zakian. 2007. “The Yeast Pif1p DNA Helicase Preferentially Unwinds RNA DNA Substrates.”. Nucleic Acids Res 35 (17): 5809-18. doi:10.1093/nar/gkm613.

Reference Link
Sabourin, Michelle, Creighton Tuzon, and Virginia Zakian. (2007) 2007. “Telomerase and Tel1p Preferentially Associate With Short Telomeres in S. Cerevisiae.”. Mol Cell 27 (4): 550-61. doi:10.1016/j.molcel.2007.07.016.

Reference Link
Vega, Leticia, Jane Phillips, Brian Thornton, Jennifer Benanti, Mutiat Onigbanjo, David Toczyski, and Virginia Zakian. (2007) 2007. “Sensitivity of Yeast Strains With Long G-Tails to Levels of Telomere-Bound Telomerase.”. PLoS Genet 3 (6): e105. doi:10.1371/journal.pgen.0030105.

Reference Link
Sabourin, Michelle, Creighton Tuzon, Timothy Fisher, and Virginia Zakian. (2007) 2007. “A Flexible Protein Linker Improves the Function of Epitope-Tagged Proteins in Saccharomyces Cerevisiae.”. Yeast 24 (1): 39-45. doi:10.1002/yea.1431.

Reference Link
Goudsouzian, Lara, Creighton Tuzon, and Virginia Zakian. (2006) 2006. “S. Cerevisiae Tel1p and Mre11p Are Required for Normal Levels of Est1p and Est2p Telomere Association.”. Mol Cell 24 (4): 603-10. doi:10.1016/j.molcel.2006.10.005.

Reference Link
Azvolinsky, Anna, Paul Giresi, Jason Lieb, and Virginia Zakian. (2009) 2009. “Highly Transcribed RNA Polymerase II Genes Are Impediments to Replication Fork Progression in Saccharomyces Cerevisiae.”. Mol Cell 34 (6): 722-34. doi:10.1016/j.molcel.2009.05.022.

Reference Link
Ribeyre, Cyril, Judith Lopes, Jean-Baptiste Boulé, Aurèle Piazza, Aurore Guédin, Virginia Zakian, Jean-Louis Mergny, and Alain Nicolas. (2009) 2009. “The Yeast Pif1 Helicase Prevents Genomic Instability Caused by G-Quadruplex-Forming CEB1 Sequences in Vivo.”. PLoS Genet 5 (5): e1000475. doi:10.1371/journal.pgen.1000475.

Reference Link
Chan, Angela, Jean-Baptiste Boulé, and Virginia Zakian. (2008) 2008. “Two Pathways Recruit Telomerase to Saccharomyces Cerevisiae Telomeres.”. PLoS Genet 4 (10): e1000236. doi:10.1371/journal.pgen.1000236.

Reference Link
Pinter, Stefan, Sarah Aubert, and Virginia Zakian. (2008) 2008. “The Schizosaccharomyces Pombe Pfh1p DNA Helicase Is Essential for the Maintenance of Nuclear and Mitochondrial DNA.”. Mol Cell Biol 28 (21): 6594-608. doi:10.1128/MCB.00191-08.

Reference Link
Boulé, Jean-Baptiste, and Virginia Zakian. 2010. “Characterization of the Helicase Activity and Anti-Telomerase Properties of Yeast Pif1p in Vitro.”. Methods Mol Biol 587: 359-76. doi:10.1007/978-1-60327-355-8_25.

Reference Link
Wu, Yun, and Virginia Zakian. (2011) 2011. “The Telomeric Cdc13 Protein Interacts Directly With the Telomerase Subunit Est1 to Bring It to Telomeric DNA Ends in Vitro.”. Proc Natl Acad Sci U S A 108 (51): 20362-9. doi:10.1073/pnas.1100281108.

Reference Link
Paeschke, Katrin, John Capra, and Virginia Zakian. (2011) 2011. “DNA Replication through G-Quadruplex Motifs Is Promoted by the Saccharomyces Cerevisiae Pif1 DNA Helicase.”. Cell 145 (5): 678-91. doi:10.1016/j.cell.2011.04.015.

Reference Link
Tuzon, Creighton, Yun Wu, Angela Chan, and Virginia Zakian. (2011) 2011. “The Saccharomyces Cerevisiae Telomerase Subunit Est3 Binds Telomeres in a Cell Cycle- and Est1-Dependent Manner and Interacts Directly With Est1 in Vitro.”. PLoS Genet 7 (5): e1002060. doi:10.1371/journal.pgen.1002060.

Reference Link
McGee, Jean, Jane Phillips, Angela Chan, Michelle Sabourin, Katrin Paeschke, and Virginia Zakian. (2010) 2010. “Reduced Rif2 and Lack of Mec1 Target Short Telomeres for Elongation Rather Than Double-Strand Break Repair.”. Nat Struct Mol Biol 17 (12): 1438-45. doi:10.1038/nsmb.1947.

Reference Link
Fachinetti, Daniele, Rodrigo Bermejo, Andrea Cocito, Simone Minardi, Yuki Katou, Yutaka Kanoh, Katsuhiko Shirahige, Anna Azvolinsky, Virginia Zakian, and Marco Foiani. (2010) 2010. “Replication Termination at Eukaryotic Chromosomes Is Mediated by Top2 and Occurs at Genomic Loci Containing Pausing Elements.”. Mol Cell 39 (4): 595-605. doi:10.1016/j.molcel.2010.07.024.

Reference Link
Zhou, Ruobo, Jichuan Zhang, Matthew Bochman, Virginia Zakian, and Taekjip Ha. (2014) 2014. “Periodic DNA Patrolling Underlies Diverse Functions of Pif1 on R-Loops and G-Rich DNA.”. Elife 3: e02190. doi:10.7554/eLife.02190.

Reference Link
Bochman, Matthew, Katrin Paeschke, Angela Chan, and Virginia Zakian. (2014) 2014. “Hrq1, a Homolog of the Human RecQ4 Helicase, Acts Catalytically and Structurally to Promote Genome Integrity.”. Cell Rep 6 (2): 346-56. doi:10.1016/j.celrep.2013.12.037.

Reference Link